As an Amazon Associate, this site earns from qualifying purchases. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The margin of safety in laying hens was conducted in 144 laying hens. At the end of the treatment phase, gross necropsies were performed on 12 hens from each group, and organs weights were evaluated. 7) Rinse the container used to prepare the 1 to 1 dilution of Safe-Guard AquaSol with additional water, and add the rinse water to the medicated water tank or the stock suspension tank of the dosing pump. The volume of water in the stock suspension container has to be calculated taking as a basis the present injection rate of the dosing pump and the volume of drinking water usually consumed by the animals over a period of 3 to 24 hours. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Eggs that have worms will also potentially infect humans and cause illnesses. At concentrations from 5 mL up to 75 mL of product /L stock suspension (1,000mg to 15,000 mg fenbendazole/L) and within up to 8 hours during the treatment administration period no stirring of the stock suspension is required. Safe-Guard AquaSol is indicated for the treatment and control of adult Ascaridia galli in broiler chickens and replacement chickens and for the treatment and control of adult A. galli and Heterakis gallinarum in breeding chickens and laying hens. Here are the various types of worms, their appearance, how theyre clinically diagnosed, and their associated symptoms: You can use Safeguard on chickens. Best Veterinary Solutions, Inc.1716 Detroit St P.O. Safeguard is a known and proven effective dewormer that can be administered daily. Accidental ingestion may cause gastrointestinal disturbances and hypersensitivity reactions in humans. At the end of the treatment phase, gross necropsies were performed on 48 chickens from each group, and organs weights were evaluated. Histopathologic evaluations were performed on the gross lesions collected during the necropsy. No clinically significant effects related to the administration of Safe-Guard AquaSol were observed for any of the parameters evaluated. PRODUCT LABEL NEW PRODUCTION TECHNOLOGY 1 Now approved for laying hens and replacement chickens intended to become laying hens Safe-Guard AquaSol was administered orally as medicated drinking water to a group of 110 breeding chickens (10 male and 100 female) at 3 mg fenbendazole/kg body weight/day (3 times the recommended label dose) for 21 consecutive days (4 times the recommended duration). 2018 Pipestone Veterinary Services. Chickens: Safe-Guard AquaSol is indicated for the treatment and control of adult Ascaridia galli in broiler chickens and replacement chickens and for the treatment and control of adult A. galli and Heterakis gallinarum in breeding chickens and laying hens. To anyone thinking of getting one of those cute little coops. The efficacy against adult A. galli and H. gallinarum was 100% and 88.9%, respectively. Use within 6 months after opening. DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. In the study, the efficacy against adult A. galli was 100%. In all chickens, feed and water intake, body weights, clinical health, and mortality were recorded. Only two pigs at the Minnesota (MN) site that were treated with FBZ had abnormal post-treatment observations ("loose stools"). A fifth effectiveness study was conducted in the US using 550 Cobb breed broiler chickens (4 to 5 weeks old). The required daily volume of product is calculated from the total estimated body weight [kg] of the entire group of chickens to be treated. A common protocol was implemented in two different geographical locations and with two different investigators. hidden 507.825.4211 (Pipestone, MN Office). | What Drives Aggression and How to Avoid It. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). Swine: A multi-site, masked, negative-controlled dose confirmation field study was conducted to provide substantial evidence of the effectiveness of Fenbendazole (FBZ) Suspension (20% w/v) administered orally in drinking water to pigs for three consecutive days to provide a dose of 2.2 mg FBZ/kg body weight daily against the dose-limiting worm Trichuris suis (T. suis). Swine: Safe-Guard AquaSol must be administered orally to swine via the drinking water at a daily dose of 2.2 mg/kg BW (1 mg/lb) for 3 consecutive days. In the study, the efficacy against adult A. galli was 100%. DESCRIPTION: Safe-Guard AquaSol is a suspension concentrate containing fenbendazole, an antiparasitic. For a better experience, please enable JavaScript in your browser before proceeding. Do not freeze. For Patent Information: http://www.merck.com/product/patent/home.html. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS, or http://www.fda.gov/AnimalVeterinary/SafetyHealth. Aquasol is 200mg fenbendazole/ml of product (20%) -> recommendations from the product bulletin and the US National Lib. Adequacy of infection was demonstrated at both study sites by having more than 6 non-medicated pigs (11 of the 12 non-medicated animals in MN and 9 of the 12 non-medicated animals in CA) with adult T. suis worm counts of 100 or more per animal. Can Corid & Safeguard AQUASOL both be mixed in water at same time? The reproductive safety in broiler breeding chickens was conducted in 220 broiler breeder chickens. In each study, 24 healthy pigs were randomized to two treatment groups (FBZ treated and non-medicated) by first blocking by weight in blocks of 4 pigs each and within each weight block, fecal egg count (FEC) in blocks of 2 pigs. Add the entire 1 to 1 dilution of Safe-Guard AquaSol in water to the water in the stock suspension tank of the dosing pump. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. A fifth effectiveness study was conducted in the US using 550 Cobb breed broiler chickens (4 to 5 weeks old). 3) Pour a volume of water equal to the calculated volume of product needed into the measuring device. Zyfend A, 30 mL. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The pivotal dose confirmation studies and field effectiveness studies demonstrated substantial evidence of effectiveness of Safe-Guard AquaSol at the dose of 1 mg fenbendazole/kg body weight/day for 5 consecutive days against adult A. galli in broiler chickens and replacement chickens and against adult A. galli and H. gallinarum in breeding chickens and laying hens. SAFE-GUARD AquaSol Poultry (270 liters/pallet) 1 x 1 Ltr. Broiler chickens, replacement chickens, breeding chickens , and laying hens . Chickens: Two margin of safety studies (growing broiler chickens and laying hens at peak egg production) and one reproductive safety study (broiler breeder chickens) were conducted. Chickens: Six pivotal dose confirmation studies and five field effectiveness studies were conducted to evaluate the effectiveness of Safe-Guard AquaSol oral suspension against adult A. galli in broiler chickens and replacement chickens and against A. galli and H. gallinarum in breeding chickens and laying hens. There were no abnormal post-treatment observations attributed to administration of FBZ at either study site. The reproductive safety in broiler breeding chickens was conducted in 220 broiler breeder chickens. Use within 6 months after opening. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS, or http://www.fda.gov/AnimalVeterinary/SafetyHealth. I generally alternate between safeguard goat wormer, and valbazen for my birds, and I always dose each bird directly and orally to ensure that the dose is correct for each. The daily dose of 1 mg fenbendazole per kg BW (0.454 mg/lb) is equivalent to 0.005 mL Safe-Guard AquaSol per kg BW (0.00227 mL/lb). Smaller particle size helps prevent sedimentation and clogged pipes, filters or nipple drinkers. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). Important: Always read and follow instructions provided by the manufacturer as concentration and dosage can change! Formulated in France. SAFE-GUARD AQUASOL (Fenbendazole oral suspension) Innovative manufacturing process enables easy, effective deworming for broilers, breeders, pullets and laying hens through oral administration via drinking water. Each study site selected pigs from one source herd verified to be free of T. suis infection. You are using an out of date browser. This thread also discusses dosing to avoid withdrawl, I've never done it this way (because I want to know for sure each bird got the correct dose), but here it is if you want to consider it: Hello again! The parasite management plan should be adjusted accordingly based on regular monitoring. In all chickens, feed and water intake, body weights, clinical health, and mortality were recorded. A sixth dose confirmation study was conducted in the US using 176 Ross breed broiler chickens (4 to 5 weeks old). What Is a Heritage Pig? A decrease of effectiveness over time may indicate the development of resistance to the dewormer administered. The percent reduction in T. suis worm counts in the FBZ medicated animals was greater than 90% (98.5% in MN and 98.6% in CA) compared to the non-medicated animals using transformed data (geometric means). Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 120 chickens (60 male and 60 female in each group) at 1, 3, and 5 mg fenbendazole/kg body weight/day (1, 3, and 5 times the recommended label dose) for 15 consecutive days (3 times the recommended duration). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Family owned since 1975. The withdrawal period refers to the time you need to take before consuming eggs produced by hens that are treated with the product, just in case the active ingredient has any effect on egg taste, safety, and quality. The efficacy against adult A. galli and H. gallinarum was 97.6% and 95.3%, respectively. It is the active ingredient used in Safe-Guard Aquasol, and it works to combat adult-stage roundworms and adult-stage cecal worms in chickens. For customer service, adverse effects reporting, and/or a copy of the SDS, call 1-800-211-3573. Housing, management, and husbandry procedures were typical of commercial production practice. Safe-Guard AquaSol was administered orally in drinking water at 1 mg fenbendazole/kg body weight/day for 5 consecutive days. Please use the following formula: Follow the instructions in the order described below to prepare the medicated water. Deworming and treatment are important to ensure and maintain the health of your chickens and prevent the emergence of intestinal parasites. The margin of safety in broiler chickens was conducted in 480 broiler chickens. For customer service, adverse effects reporting, and/or a copy of the SDS, call 1-800-211-3573. Safe-Guard AquaSol, a medicated feed for chickens, is FDA-approved for the treatment and control of cecal worms in poultry. for 5 consecutive days. In this case, you would have to deworm your older chickens first before deworming the baby chicks. Zhejiang Apeloa Kangyu Pharmaceutical Co., Ltd. You can check your chicken for worms and approach to deworm them with the following approaches: It is recommended to deworm chickens regularly as it will work as a preventive measure against infestations. A decrease of effectiveness over time may indicate the development of resistance to the dewormer administered. Palatability: A pivotal palatability study was conducted to evaluate the palatability of 20% Fenbendazole Suspension in pigs through voluntary consumption of medicated water when offered for approximately 5 hours a day over 3 consecutive days at a dose of 2.2mg fenbendazole/kg body weight (BW) per day (label dose). Each mL of Safe-Guard AquaSol contains 200 mg of fenbendazole. Do Hens Need a Rooster to Lay Eggs? GTIN#/UPC#. All dewormers require accurate dosing for best results. Each mL of Safe-Guard AquaSol contains 200 mg of fenbendazole. SAFE-GUARD AQUASOL- fenbendazolesuspension The daily dose is 2.2mg fenbendazole per kg BW (1 mg/lb) which is equivalent to 0.011mL Safe-Guard AquaSol per kg BW (0.0045 mL/lb).The required daily volume of product is calculated from the total estimated body weight [kg] of the entire group of pigs to be treated. Unlike your options for chicken mite treatment, there are only two FDA approved products available for deworming chickens. [Note: If more than the required amount of the product is accidently poured into the measuring device, discard the entire contents and repeat the process from Step 3 above.]. The efficacy against adult A. galli was 90.2%. Safe-Guard AquaSol is a suspension concentrate containing fenbendazole, an antiparasitic. Contact your veterinarian for further assistance in the control and treatment of worms. Do not use the drug inlaying hens. Deworm only when theres a high concentration of worms in your chickens. Proprietary, innovative wet-milling technique produces highly stable suspension in drinking water. Now approved for laying hens and replacement chickens intended to become laying hens, Proprietary, innovative wet-milling technique produces highly stable suspension in drinking water, Smaller particle size helps prevent sedimentation and clogged pipes, filters or nipple drinkers, Easily administered by medicators or proportioners, 98.8% efficacy against A. galli in 4 US field studies (100% in broilers), 92.1% efficacy against H. gallinarum (long lived birds), No pre-slaughter withdrawal period when used as directed, Shelf life of 3 years unopened, 6 months after opening multi-use container reduces waste, No adverse effects on egg production, hatchability or progeny of breeders, No impact on water or feed intake compared to unmedicated controls. It is also available as a water-soluble paste for feeding chickens. The reproductive safety in broiler breeding chickens was conducted in 220 broiler breeder chickens. Stir until the content in the stock suspension tank is visibly homogeneous. Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a daily dose of 1.0 mg/kg BW (0.454 mg/lb.) It is specifically indicated by the manufacturer that Safe-Guard Aquasol should not be used for laying hens and replacement chickens that are groomed to become laying hens. Another group of 36 hens was provided non-medicated drinking water and used as a control group. A fourth field effectiveness study was conducted in the US using 550 Cobb breed breeder hens (63 weeks old). Non-medicated water consumption of the pigs in each treatment pen was measured prior to treatment administration to estimate the amount of water required for dosing on each day of the treatment period. A natural field isolate of T. suis collected in April 2010 from a sow located on a commercial farrow to wean operation located in the U.S. was used. Loading reviews. INDICATIONS: Safe-Guard AquaSol is indicated for the treatment and control of adult Ascaridia galli in broiler chickens and replacement chickens intended to I happen to have a 10 ml pipet and a 100 ml volumetric flask as well as 1 ml and 3 ml syringes so it's rather simple for me to do the dilutions. Fenbendazole (active ingred.) The medicated water must be prepared daily prior to each administration. Swine: Safe-Guard AquaSol is indicated for swine, except for nursing piglets, for the treatment and control of: Lungworms: Adult Metastrongylus apri, Adult Metastrongylus pudendotectus; Gastrointestinal worms: Adult and larvae (L3, L4 stages, liver, lung, intestinal forms) large roundworms (Ascaris suum); Adult nodular worms (Oesophagostomum dentatum, O. quadrispinulatum); Adult small stomach worms (Hyostrongylus rubidus); Adult and larvae (L2, L3, L4 stages - intestinal mucosal forms) whipworms (Trichuris suis), and Kidney worms: Adult and larvae Stephanurus dentatus. Once opened, do not store the container above 25C (77F). Fenbendazole (active ingred.) Safe-Guard AquaSol was initially approved in October 2015 for the treatment and control of adult A. galli in broiler chickens and replacement chickens intended to become breeding chickens and for the treatment and control of adult A. galli and H. gallinarum in breeding chickens. Chickens: Two margin of safety studies (growing broiler chickens and laying hens at peak egg production) and one reproductive safety study (broiler breeder chickens) were conducted. At concentrations of up to 5 mL/L stock suspension (1 g fenbendazole/L) no stirring is required. The goat wormer is not formulated to mix well in water and will settle out over time as it sits, and the dosing will be compromised greatly. A field effectiveness study was conducted in the EU in a flock of 13,244 Hy-Line layer breed replacement chickens (13 weeks old). Dosage and Administration Safe-Guard AquaSol must be administered orally to chickens via the drinking water at a daily dose of 1.0 mg/kg BW (0.454 mg/lb) for 5 consecutive days. The parasite management plan should be adjusted accordingly based on regular monitoring. 2) Select a measuring device capable of accurately measuring a volume of at least twice the calculated Safe-Guard AquaSol daily volume. Safeguard is usually administered orally, I do it with an oral syringe. The following formula should be used to estimate the dose: Total estimated body weight of the chickens in kilograms x 0.005 mL = amount of Safe-Guard Aquasol to use in milliliters in a day. At the end of the treatment phase, gross necropsies were performed on 12 hens from each group, and organs weights were evaluated. After complete consumption of the medicated water, the animals should have access to non-medicated drinking water ad libitum. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Only two pigs at the Minnesota (MN) site that were treated with FBZ had abnormal post-treatment observations (loose stools). In the study, the efficacy against adult A. galli was 99.4%. The efficacy against adult A. galli and H. gallinarum was 97.6% and 95.3%, respectively. The chickens were necropsied 7 to 8 days after the last treatment, and adult worms in the intestines and ceca of the chickens in the control and treated groups were counted to determine percent efficacy. USER SAFETY WARNINGS: Not for use in humans. The large roundworm, Ascaridia galli is the most common intestinal parasite found in backyard and free range chicken flocks worldwide. The two pigs with the two lowest FEC counts within a weight block were randomized one per treatment group and the two pigs with the highest FEC counts within a weight block were randomized one per treatment group. At concentrations from 5 mL up to 75 mL of product /L stock suspension (1,000 mg to 15,000 mg fenbendazole/L) and within up to 8 hours during the treatment administration period no stirring of the stock suspension is required. Hematology and clinical chemistry parameters were evaluated in 12 hens from each group. This is equivalent to 0.005 milliliters of Safe-Guard Aquasol per 1-kilogram chicken body weight in a day for 5 consecutive days. Be careful to avoid any accidental spill or loss of 1 to 1 dilution which may inadvertently result in less than the required dose of fenbendazole. There was a significant treatment effect in T. suis worm counts between medicated and non-medicated treatment groups at each study site (p=0.0006 in MN and p=0.0003 in CA). Please use the following formula: Total estimated body weight [kg] of the chickens to be treated x 0.005 mL = mL Safe-Guard AquaSol/day, Volume of Safe-Guard AquaSol (for 5 days). The medicated water should appear hazy. Three dose confirmation studies were conducted in European Union (EU), using 105 Rhode Island Red breed hens (2 years old) for each study. Histopathologic evaluations were performed on the gross lesions collected during the necropsy. Safeguard is a known and proven effective dewormer that can be administered daily. Safe-Guard AquaSol was administered orally as medicated drinking water to three groups of 36 hens at 1, 3, and 5times the recommended label dose (1, 3, and 5 mg fenbendazole/kg body weight/day) for 15consecutive days (3 times the recommended duration). Proprietary, innovative wet-milling technique produces highly stable suspension in drinking water, Smaller particle size helps prevent sedimentation and clogged pipes, filters or nipple drinkers, Easily administered by medicators or proportioners, Heterakis gallinarum (adult stage cecal worms), 98.8% efficacy against A. galli in 4 US field studies (100% in broilers), 92.1% efficacy against H. gallinarum (long lived birds), No pre-slaughter withdrawal period when used as directed, Shelf life of 3 years unopened, 6 months after opening multi-use container reduces waste, No adverse effects on egg production, hatchability or progeny of breeders, No impact on water or feed intake compared to unmedicated controls. Adult-Stage roundworms and adult-stage safeguard aquasol for chickens worms in your browser before proceeding were evaluated calculated volume of equal... Chicken flocks worldwide medicated feed for chickens, breeding chickens was conducted 144... 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